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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee59b63f2a4ac3603e198f9ca355406e3ab268874d941c7be465c91c94a4b1f' 
  AND token = 'OzK6xJ/9qrU3pbAx11HJGaQjGBaqIRMny9NrG8j8NRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}