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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413e9da3c3f0796a11b389cfa76f4aa081a0587b4b6e62b109b4a5c24591f66d' 
  AND token = 'gGPdzUKEN1tsYai98VJZxWsdP1azRjAjFPxrHgyfLJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}