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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aafc4ad203d004ab47cb8c915de537eb910f6a2f1e76e20207150a4a3375d02c' 
  AND token = 'u3s0fmlc04eYcBvrzFbdJnN0UuFM2+HYx0KuL+BQa+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}