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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c9eb27dc21dfb11e3b2382b617471de3935acc0e911a0387eb3a3af37d958c' 
  AND token = 'a/jQom2uWIzpR2rzqfQu7QSmFqP7PTzWPS3Lynv2lCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}