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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f58b9cef8c98671dcf72e0219c5f7fee09a561f10a885ce57b4bc6d6366ecd0' 
  AND token = 'h6mqfYJ90WuhJx9cuKiY6D5nQLhGqqUr+sfRIPVa19U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}