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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06db48f65493e2e84ac8f10717edf41f51f77d07d37e1a444f21db8662a0ebee' 
  AND token = '7zV+SSZf6S0utKvgA0KjsQ1XyRQ9fZCwTWsMp30D6d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}