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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7164521e9aceed6bb683dafacb55d43b51475301a75e350bef1fdd60ebe4f4' 
  AND token = 'yYF0g58qUMTVy1vUBFX5XiBY8/Q23lMycYEUUJCKIuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}