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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3786efabc9bda7ea4e194d9c15de2263ad9212c325d7a66877b54f3fb6c002' 
  AND token = 'McYF1XBb3XiXCNHgTSyEV/3eS0l0vrrIUYo1+JSmUAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}