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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bc1eebf5861f0df32ca744fd5c20eabdf10ce1fc09da8257ab40a7a161e2c61' 
  AND token = 'tIt/NaPPtOGANwB3lAnAfEb8Xkp+zxVonCnoFAB4ZFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}