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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149480d4694859fac972d4492e26974c164793e310cc4d1257af481a49e5292c' 
  AND token = 'c05cQ/ODMDp17iXeLh/+Z+yZnQB3a3SyS9m2iRqO9dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}