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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d9923de7988d5041e4512be5622ff5b91a9526f87f44c6bbcb98b23c17355d' 
  AND token = 'iWSwdumm3tGXVvcaSJ6wlepEW43fBvtqTR50yCX08dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}