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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f378f7c03835a1b9395dae013a4e918fd4027227a590bc93c30804f1ebc56ff' 
  AND token = 'KPmFgA+72YDSslrEgQQmg2dyW4Zk8C42gkRdKcSpj8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}