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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7d86ff0d39a8cd0b225f70c2da7ab03ad4caf2efea14b2980580d711efd399' 
  AND token = 'AxgaxMYHMtOUyQUD+9QgegG2UaMe8dZqeRI5yiv9O/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}