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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f721b97457b0060e329cbe67b7265e4b4877ef0206ed01ed5a4ed075f211ab' 
  AND token = 'B4lds6gVSFQ3/LIb6/aU8Yqs6oBRA+FvVtdp3Vk/I/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}