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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e22ec9b5cb5c3163f381221aa69e183d2445f933a33428c5050b04785df2a4e' 
  AND token = 'uIIgMNKRQpSa3HChWUeY4zY5ItuS6SrVL+3UDw9MfpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}