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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64c40eb3c28cd5002b5c73212250dcd731c70eccd3f55931f2adbdf3a6b7cac' 
  AND token = 'erWAWEA/AGFmUKUB/YbQ3rrp+TDfNP5dVUdxlR+13lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}