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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4f656725c631b42fdee4779f9b54aabe8e5a1b3a95411cab6760ab1f1fb421' 
  AND token = 'v9xv4+raZwU8/+7kbMGECTxcJsW9ezTffdgnohZHMpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}