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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a10e273b0d865b9e367bb5a701145742d93951c511c3200050e15e9772f8112b' 
  AND token = 'PrxwRpEuoinpadUQljMZ+5M0RoLpu8QJv5PCEh5WkfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}