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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b584c04b87f3fc65039c1bc6452a42d10cf407412a6c1fc487f9f168c4c578a' 
  AND token = '65U5JTVBXqbAf7zD6eLkYDDSFf2p7pbNKBUOFPhRLb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}