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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '818c82639df37e2bc861ee6a3973105f0841e9ecb4ee0f5a6650c66caced0776' 
  AND token = 'OdK56wZ9KO+yxBIG+sF/pBq8qME1PBS9ksCbrTqAE88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}