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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eb4dee6ae2824e5fc9720a8e204dfd2ffc508ea9266458b7671a18411b738da' 
  AND token = 'EJ3izAJg/Lq7Ta2/HNzlzfNnZy/0vDzH7qUcak6lymM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}