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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2222e8fa9f8e0843a488274f3231ede86953110a3c2c79b4b56ad867033b3a9' 
  AND token = 'rhiL2gnbLNQSkMbPVUbYGaw1qPfSxK3C0DW+G81BwgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}