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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a325b187d5b4d2840c3c0ae60ece8df94119b18d84b47108720b31ed2e35eda4' 
  AND token = 'NNXdUzdq7MiYtiHULeK90MYUq7M/3+yyx+LYQ0Kv07U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}