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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9ffeba205d73d23fa004b61069abbfb93563f71d7218a05036b26d46d431bb' 
  AND token = '79fES8xFm/3XgXLTMkBQlJWZhKX8FUuwZHc0rB7ausQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}