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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0f3d37ffcc930ed21ba6a66a851c3e0f0d96817a8a23d4024d119103c99605' 
  AND token = 'CudzUE3owAP53/tftMjEK//TTwGsrawH0mwZynefJoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}