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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3be2d3b88ab60232eb2a531ac76eefb59aac5c0cb504758e0414e07d2c4aaae1' 
  AND token = 'IU26vcGMjBQrdbKMF0bw89uLZ9msBSxVjAF9ff4PueI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}