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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64682108552be5cac3f652bf1de68a93f7d48d85f45caee18c039fa341afb0ed' 
  AND token = '8hJ0CeX4QgCahUGOxxeJ7dc4JOmz6vDCFENnZZDa+VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}