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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43935a0e60eb63109ea077b7a6cefbaaeaf315a2c9505312df1ffc200a426194' 
  AND token = 'qx3ruFimRRWMWoOdf8X1c+gG4wv5m3ldwt4qY+M2a2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}