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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1930308f5e8a764c7057cbd1761953014345deb83a9d3dd40f2f6e3b70c00b' 
  AND token = 'JES4+t2/2IqTqfokaKU4o69ByMRIewIVrMkqU8iwiJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}