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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b595ccfd2ff37c6a4b6d91e41f880f6cc6b829cab3ed09b87600992e5d4cafa' 
  AND token = 'tw9SYsg0peqn/j31a7VRVdgpIVKY0Dz4X3TkHTEMlxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}