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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab29114209513086520163f9b7516e3e97982206da780efb8f14678e647ebab' 
  AND token = 'bo8Apx4tGnyODPOCVcNLL8wtVhhn+hbMUnaWXWbJAnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}