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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8bd5a5552f59205c28a79a1edc72a5b516feec65bde5cd6af47c0c66cd1fe7b' 
  AND token = 'Q2cbW6r+n8Sm6vsDYbpO+nXHg8egX798MYjzrEQDbU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}