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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f9af11be91eb3225533071a909cc50550a7bdfc7a7188bfa5b5a40eb70bab2' 
  AND token = '4JirFDM6iXguryhs9K/p4Fws4nNFQc1ZqPhpB1L0jSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}