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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38ef180c4cd42f0d06865309c84b829f7a260ac2a2c4ee2520f1c7ce899bb4ac' 
  AND token = 'p4gB/CE08ShfhQQlTjgA9q1YeYCY6eYiJPoAnMZn77k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}