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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '876533c4165f68336c6cde226747d421dd38cb348918fb6df5873958cc6c962d' 
  AND token = '+hMZNRQr9xheVQYEVXFq+/Qq4GEirGMyo5G3mOMfmYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}