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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b93b0ef4da5e919f8787ff9b678a7644b8a96627380309b27020703e132eb3' 
  AND token = '8t4FT9WaC/M8wouHVeo9NaUy/kiE0GRBAH4kflHCpk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}