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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e7833241bb627264bb3aacf63d23655c2d8b988324059bd32898d32ef8e21e' 
  AND token = 'iGkTEUdQ6EoJw+SzGWeyO9mw0f4ZE7NjM3WGNzUG3aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}