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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a40a645a98dd298239d817f5df901b4cc8ef8ab29cc4ae587083bb2d9f4de11' 
  AND token = 'u3AqtUqomleOXk1MX8ZzgzKrcbFpftg6BmNhJ+1V22I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}