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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9894e6c76d2e4e317b4485a614325119c54bbedb52e8afdfcc67d50d2e96291' 
  AND token = '3E1bOx6st/EjW5zi3uHQ9qTVC0X/pW1PWf4SrDoM5gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}