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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de387df3787b61c51cab33dd3e087181f75ddfc692cffc4e23bdb5a65fb75c90' 
  AND token = 'vV+t3K2XXxi0MGHkXtSgcAw0EcRmriPFZxt52wsQs9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}