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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8611def87b0e585773d1f55d48ceb849f03bae82b2e30fa5f47ba185206835c' 
  AND token = '3JyrXD0uXXw16aVAb/M/lUg9WxbuVlNmbpfUsh1snHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}