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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a75cf65d460ea0add9f87005cb92fcb51c933e94aa96319c4198abb3a8af29' 
  AND token = 'XTaVD70z7ptSUI0NYMuAIqDH+GDQxJcGIBofY83IReo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}