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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cc57a85697e145590b869fafb421d3b294d2cf2680e6fff3195e1a732a1074e' 
  AND token = 'uPyxDla3pSPIu+9HGh6mTfApYeLV4JLi7OYg3RMYXoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}