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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec0ef4c72980e87d6ab17c39ec8f4f89cf4891ea7d782677125fad718307c7a' 
  AND token = 'HxzQFdrHUvsnzA/HWO7IBSMwDCTtbfP8QtxrRqekHSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}