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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290b1c746a7f0b7d1970fa5f1779f6e5ddbaa564be31dce1c1d55c5cfd786b6f' 
  AND token = '0BtsolbniDHcxMMGV0x1zpBc1sjCsXoUoI1v3R4/BSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}