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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c146f0978ce2625d93a4c85f990b065e5fade163d065f518b992cd14f4c03b' 
  AND token = 'mW/T+N4t9TEs5skQ+bHUDZnxx9zsTEtjTnJZcAkowYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}