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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434cf30a31b2646e0390b69aeaf1f40beb90fe92f289441577424b341d810bf6' 
  AND token = 'nO9roKt3v1X/ixHuwfWen13tUOnRHVPEiLWyaGw78Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}