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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fce6afd173d6c46a6093c3b153626a4f345326afa41b51d17f681cb85b7a5ec' 
  AND token = '0rGaS/6/Lx+rGMxMFLV7hOiPLBmwuLhRSIAyzOUnm70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}