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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f946a88d66d1fd47afe1f3fddc52e8755343d1d890fd1fb75df46b038042d288' 
  AND token = 'szyDTe2uYInroHn8cyMMRZDU1WJPI3VZYo6+ZSAhRvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}