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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb7df21a28adef13186be5a130a1064124557e87a8bf3c3086735dc5437f3360' 
  AND token = 'FYkHB7lBDenEcgIMu0PDjuX8cE5M8cvoV2MCLP6VZ0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}